This discovery owned by three independent research centers of America, the Netherlands and Austria .While in collaboration, they were able to discover hitherto unknown and rare disease associated with a decrease in brain size, leading to disruption of motor activity and cognitive function, and so on. already known that genetic mutations associated tRNAs are the cause neurological diseases in childhood.Regarding CLP1 gene mutations in a protein, they will lead to the death of motor neurons and muscle paralysis.Studies have shown.What children are almost all families of the subjects were born with neurological problems were carriers CLP1-mutations.These mutations are clinically manifest microcephaly, cortical dysplasia, mental retardation, impaired cognitive and motor functions, as well as seizures.
And this disease can not be diagnosed in the old, based on symptoms and clinic.To put this diagnosis is necessary to identify a mutation in a gene CLP1.
There is another recently discovered diseas
knowledge of this level will give the opportunity to protect motor neurons from death and other neurodegenerative problems.
Caffeine in the fight against Alzheimer's
Not long ago a group of scientists discovered that caffeine is able to curb excessive phosphorylation of tau protein.Tau proteins are a hallmark of neurological disease Alzheimer's.Conducted over two years of research, provide an opportunity to create a new class of drugs that could stop Alzheimer's development.Contained in tea, coffee and cocoa caffeine is an antagonist of adenosine receptors of the brain.Adenosine has a calming effect on the processes of excitation in the brain.A caffeine on the contrary, makes the brain receptors to be on our toes.
And that blocking the adenosine receptors is the key to the suspension of developing Alzheimer's disease.So, given the data, scientists have identified a water-soluble substance ultrasensitive antagonist.It turned out to be better than just caffeine, as had fewer side effects and only affected adenosine receptors.
After a successful study of the drug on mice, the scientists plan to continue these studies in other animals, and then, if successful, to proceed to clinical trials and the development of a more perfect product.
Electrical stimulation of the spinal cord - a chance to get on their feet
Clinical trials on men, which was implanted in the spinal cord pacemaker, finished the restoration of motor function and functioning of the intestines, and the genitourinary system, avoiding neurological disease andparalysis.
electrodes are implanted into the epidural space containing connective tissue and venous plexus.From this position occurs electrostimulation ganglia, which are responsible for the movement of the lower limbs.
another study has recently been carried out, which resulted in four male subjects regained the ability to move, improve the general condition of the owl, build muscle and resulted in blood pressure back to normal.
Two of the four men had been diagnosed with a complete spinal cord injury, not giving any chance even to the slightest recovery.
The use of this method does not require reliance on neyroreaktsionnost, as evidenced by a series of successful tests.