far ahead of advanced genetic engineering and regenerative medicine, where success lies in the fact that the opportunity to restore the damaged organ by means of the same cells.
- 1 Create authorities bioengineered way
- 2 Obtaining stem cells
- 3 Application in clinic
- 4 Print authorities via printer
Create bioengineered organs
way past 2013 was marked by the fact that it was created several organs using bioengineering techniques using human cells.Made authorities, however, is not working in the human body and in the bodies of laboratory animals (mice and rats). During this miracle bioengineering researchers used an animal carcass body was removed from his native cells and human cells were seeded brainstem origin.
These miracle-bodies include bioengineering bud cultivated with kidney rat carcass, populated epithelial cells from human kidney.It has been successfully implanted in the animal, and worked to implement the provisions it functions: filter
Obtaining stem cells
in this area (the use of stem cells) marked another success scholar Shukhrat Mitalipova, who was able to get into the laboratory embryonic stem cells Human Stem origin by means of transplantation of the nucleus ofa somatic cell into an egg .This was for cellular medicine major breakthrough as possible to create stem cells, rather than trying to get them in all possible ways.This success Mitalipova was named the journal Science as the scientific breakthrough of the year.
Application in clinic
Although these technologies is being improved in the laboratories, but regenerative medicine has already made a step forward in the direction of the clinic, where she began to be used successfully with its help it is possible to save life.Paolo Macchiarini in his hospital carries out recovery operations on the trachea, and in 2013 was first saved the life of a child with the help of bioengineered trachea.It was created on a special frame made of a material through which the trachea can be extended with an increase in the growth of a young patient.Rejection is avoided because when you create are used stem cell transplant child, so that the transplanted organ by the body of the child is not perceived as foreign.Russia also conducted such operations at the Center for Regenerative Medicine.
to success in the practical application of stem cell technology also include a unique case.German doctors were able to bring the child out of the coma and vegetative existence, using stem cells from umbilical cord blood .After replanting them in the child's condition very quickly appeared and began to build up a positive trend, the patient can begin to walk and talk.Scientists have explained the fact that the transplanted cells migrated into the brain, where they could replace missing and damaged neurons.
Print authorities using the printer
However, the most incredible achievement in the field of regenerative medicine - it is printing with help of 3D-bioprinter.Although viable whole organs and scientists still can not be created using this method, however, progress in this direction significantly.For example, an important practical step towards the achievement of medicine and began printing bronchus child.During the operation of the bronchus fragment was used in the form of tubes, made individually for the patient, it is made a successful transplant and engraftment.In Russia in 2013 it was created the first laboratory for the study of methods of three-dimensional bodies biopechati.The aim of the scientists, it was headed, was the cloning of human kidneys.The intermediate stage of the creation was called nephron.